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Outcomes of Other Medicines on VIAGRA Sildenafil metabolism is principally mediated by CYP3A4 (main route) and CYP2C9 (small route). Consequently, inhibitors of these isoenzymes may reduce sildenafil clearance and inducers of those isoenzymes may possibly enhance sildenafil clearance.VIAGRA has systemic vasodilatory Attributes that resulted in tran